- 3D-reconstruction of osseous structures and soft tissues using CT and MRT data
- Point cluster surface generation, eg. from laser scans
- Transfer of discrete polygon surfaces into CAD enabled NURBS free form surfaces
Equipment
Cell culture laboratory
- In-vitro testing of potential implant materials on human primary osteoblasts and chondrocytes
- Vitality tests (WST-1, LDH, Live/DeadTM staining)
- ELISA (Pro-Kol 1 or 2, BAP, MMP, apoptosis)
- Magnetic bead-based multiplex technology (cytokines, MMPs)
Finite-Element-Analysis
- Evaluations concerning implant dimensioning (design) and reliability
- Analysis of implant micro motion and primary stability
- Biomechanical investigations concerning osteosyntheses systems and 3D-scaffold applications
- Evaluation of range of motion, impingement and luxation behaviour
- Parameter studies concerning implant positioning and material
- Dynamic analysis of the impact process during implantation of implants
Wear Investigations
- Hip endoprostheses wear investigation ISO 14242-1
- Knee endoprostheses wear investigation ISO 14243-1
- Abrasive wear test between implant surface and bone cement (laboratory test protocol)
- Abrasive wear test between implant surface and artificial bone using geometrically simplified test samples (laboratory test protocol)
- Particle analysis according to ASTM-F1877
- Standard test for impingement of acetabular prosteses according to ASTM F2582-14
Cell culture laboratory
- Cell culture laboratories (Cultivation of human primary osteoblasts, chondrocytes, fibroblasts as well as monocytes)
- Incubators with option of hypoxia
- Dynamic cell culture
- Light, phase-contrast and fluorescence microscopy
- CytoViva Hyperspectral enhanced darkfield microscope system
- Micro Sensor technology for pH and O2 measurements
- Plate reader for fluorescence analyses
- High hydrostatic pressure module for cell and tissue experiments
- Homogenisation for decomposition of tough samples
- Homogenisation by sonication
- qTower die Real-Time PCR applications
- Lyophilisation
- Test systems for biophysical stimulation
Test equipment
- Universal test machine Zwick Roell Z050 - 50 kN
- Dynamic test machine Instron (100 Nm/ 25 kN)
- Tribology test: hip simulator (Endolab GmbH, Rosenheim, Deutschland)
- Tribology test: knee simulator (Endolab GmbH, Rosenheim, Deutschland)
- Test facility for determination of implant bone interaction and fabrication of wear particles
- test facility for orthoses and dislocation in hip
- Micro- / nanoindenter