- 3D-reconstruction of osseous structures and soft tissues using CT and MRT data
- Point cluster surface generation, eg. from laser scans
- Transfer of discrete polygon surfaces into CAD enabled NURBS free form surfaces
Equipment
Cell culture laboratory
- In vitro testing of implant materials using human primary osteoblasts, chondrocytes, PBMCs, and fibroblasts (including eluate testing)
- Viability assays (WST-1, LDH, live-dead staining, apoptosis/necrosis, cell counting)
- Immunohistochemical staining and microscopic analyses (phase contrast, fluorescence, dark field, electron microscopy)
- (Multiplex) ELISA (collagens, cytokines, chemokines, bead-based)
- Gene expression analyses and OMICs (differentiation, inflammation, signaling pathways)
Finite-Element-Analysis
- Evaluations concerning implant dimensioning (design) and reliability
- Analysis of implant micro motion and primary stability
- Biomechanical investigations concerning osteosyntheses systems and 3D-scaffold applications
- Evaluation of range of motion, impingement and luxation behaviour
- Parameter studies concerning implant positioning and material
- Dynamic analysis of the impact process during implantation of implants
Wear Investigations
- Hip endoprostheses wear investigation ISO 14242-1
- Knee endoprostheses wear investigation ISO 14243-1
- Abrasive wear test between implant surface and bone cement (laboratory test protocol)
- Abrasive wear test between implant surface and artificial bone using geometrically simplified test samples (laboratory test protocol)
- Particle analysis according to ASTM-F1877
- Standard test for impingement of acetabular prosteses according to ASTM F2582-14
Cell culture laboratory
- Cell culture laboratory (cultivation of human primary osteoblasts, chondrocytes, fibroblasts, and monocytes)
- HERAsafe 2030i 1.2 EN 12469 safety cabinet & CO₂ incubator CB 170
- Dynamic cell culture
- Light, phase-contrast, and fluorescence microscopy
- CytoViva® hyperspectral dark-field microscopy system, DFG major equipment (INST 264-176-1 FUGG)
- Test systems for biophysical stimulation (including function generators, oscilloscope)
- Multimode microplate reader
- qTower for quantitative real-time PCR applications
- High hydrostatic pressure chamber for cell and tissue analysis
- Freeze-drying system
- Microsensors for pH and O₂ measurements
- Homogenizer for breaking down hard samples
- Ultrasonic homogenizer
Test equipment
- Universal test machine Zwick Roell Z050 - 50 kN
- Dynamic test machine Instron (100 Nm/ 25 kN)
- Tribology test: hip simulator (Endolab GmbH, Rosenheim, Deutschland)
- Tribology test: knee simulator (Endolab GmbH, Rosenheim, Deutschland)
- Test facility for determination of implant bone interaction and fabrication of wear particles
- test facility for orthoses and dislocation in hip
- Micro- / nanoindenter
- Roll-slide test rig
- Dynamic 3D analysis system PONTOS (GOM mbH, Braunschweig, Germany)
- Measurement system for recording relative movements (LVDTs) and deformations (strain gauge system)
- Surface roughness measuring device
- AMTI VIVO joint simulator, DFG (INST 2268/17-1 FUGG)
- Keyence 3D laser scanning microscope VK-X260 (GHS-15-0016)
- Digital microscope VHX-6000 (GHS-16-0002)
- Digital microscope VHX-X1 with material analysis unit EA-300 (WIG-24-0050)
- Electrodynamic testing machine Zwick LTM5 (5 kN)
- 3D printer Hydra 16A
- Particle measurement device IZON qNano Gold
- Compact vibration isolation system halcyonics_i4
- Rheometer MCR 102